GUIDELINES FOR CFXF FRAGILE X RESEARCH TRANSITION AWARD

The CFXF Fragile X Research Transition Program provides support that will enable post doctoral researchers to continue fragile X research at a new research situation after postdoctoral studies are completed. In so doing, CFXF hopes to increase the number of fragile X investigators and projects worldwide, particularly at facilities that currently have no established fragile X research.

A) GUIDELINES FOR APPLICANTS

1. Length of Fragile X Research Transition Awards
   Fragile X Research Transition Awards are made for periods of two (2) years, the first two years after an individual's post doctoral studies. During this period, the applicant must spend at least 50% of full time professional effort conducting the fragile X research.
   
2. How to Apply
   a) Applications may be submitted year round, at least six weeks prior to proposed start date in the format described below in Section F.
   b) Application cover page and budget sheets are available at www.cfxf.org
   c) All copies should be submitted according to the specific directions at www.cfxf.org.
   d) Decisions on awards will be announced approximately eight weeks after receipt of the completed application.

B. ELIGIBILITY

1. Research Areas
   CFXF's goal for all of its fragile X research is to support basic research that is focused on one or more of its priority areas as identified by the CFXF Board of Scientific Advisors and the broader Fragile X research community. Those areas include:
   
   • The study of FMRP/RNA/Protein interaction
   • Reactivation of the FMR1 gene, and the epigenetic mechanisms that cause inactivation
   • Transcription and translation of FMR1
   • Translational work merging science and medicine
   • Neuroimaging
   • Neuropsych studies
     
2. Applicant Guidelines
   1. A scientist from any country may apply for a Fragile X Research Transition Award.
   2. Applicants must have a research doctorate (Ph.D.) or a doctoral degree with equivalent experience in research at the time of application.
   3. Applicants must demonstrate significant training and experience in fragile X research and must be committed to continuing fragile X research as a principal investigator
   4. The primary goal of this program is to provide support that will enable investigators to continue fragile X research in a new research situation after postdoctoral studies are completed. Ideally, the recipient will bring fragile X research to a site that formerly had none.

C. ELIGIBLE EXPENSES

1. Salary
   CFXF will provide 50% of a full-time, 12-month staff appointment, up to $20,000. The total salary must be consistent with established salary structure at the institution and with salaries actually provided by the institution from its own funds to other staff members of equivalent qualifications, rank and responsibility in the department concerned. There must be no less than 50% effort devoted by the grantee specifically to fragile X research.
   
2. Research Support
   An additional $5,000 may be provided for research expenses such as expendable supplies and equipment that may be required to pursue the fragile X research plan. The equipment must be specified at the time of application and may not be used for other purposes.

D. REVIEW OF APPLICATIONS

1. Review Process
   All applications will be reviewed for completeness and technical requirements by CFXF staff. Incomplete applications and those that do not meet the technical criteria listed herein will not be considered. A CFXF Review Committee will review all other applications.
   
2. Review Criteria
   The main review criteria are the originality and quality of the fragile X research proposed, the accomplishments/potential of the applicant, commitment of the new facility to the applicant and the project and the commitment by the applicant to continued fragile X research.
   
3. Notification of Award
   Applicants will receive written notification of the outcome of the review process.

E) ADDITIONAL INFORMATION AND REQUIREMENTS OF AWARD

1. Each recipient must submit a report to CFXF at the end of each year of the award.
   
2. CFXF may request reimbursement of any part of the award in the event that the applicant is unable to fulfill his/her commitment.

F. APPLICATIONS
All applications must be submitted in the following format:

        SECTION I

1. Cover page (CFXF Form CFXFC1) available at www.cfxf.org.
   
2. Curriculum vitae
   Please provide a short CV, covering recent time period, and a list of the names of scientific supervisors, the dates of study and complete name of the institution.
   
3. List of Publications
   List no more than five publications in order of date.
   
4. Past and Present Fellowships
   List any other fellowships or awards in the past three years, the duration, names of host institutions, supervisors and funders.
   
   SECTION II
   
5. Research Project
   In narrative form, please explain the research project in a simple, concise summary page.
   
   Then, please describe the research plan in further detail including:
   
   • the CFXF priority addressed from Section B.1
   • the significance of the project to fragile X research
   • the specific goals and aims of the project including benchmarks
   • the project areas that will provide development in the specified CFXF interest area
     
6. New Facility Information
   Please indicate the name of the department or laboratory and the institution or university at which the applicant will be employed during the grant period. Please include independent verification of employment from the facility.
   
7. Budget - Please complete Forms CFXFB3 and CFXFB41
   
   1. Salary
      CFXF will provide 50% of a full-time, 12-month staff appointment, up to $20,000.
   2. Research Support
      An additional $5,000 may be provided for expendable equipment and supplies

Application Cover Page	CFXFC1
Conference Travel Fund Budget Form	CFXFB1
Short-Term Fellowship Budget Form	CFXFB2
Budget For Initial Budget Period	CFXFB3
Budget for Proposed Project Period	CFXFB4
Budget Narrative	CFXFB5